Treatment of Human Brucellosis — Review of Evidence from Clinical Trials

Unresolved issues remain surrounding the treatment of human brucellosis. The present work aims to provide useful information to help clinicians make decisions when treating brucellosis patients. Information based on scientific evidence from clin‐ ical trials published over the past 30 years has been compiled and presented in an up‐ dated form, covering both focal and non-focal, or uncomplicated, human brucellosis. This chapter shows that, despite the studies published in recent years, areas such as the role of monotherapy or treatment in cases of focal disease, have not been ade‐ quately addressed in clinical trials, and demonstrates the need for further research.